Current Research Activities2018-09-13T10:08:02+00:00

Religious Orders Study

More than 1,100 older religious clergy (nuns, priests and brothers) have agreed to medical and psychological evaluation each year and brain donation after death. Researchers are using information from the study to discover what changes in the brain are responsible for memory and movement problems. The study also looks closely at the transition from normal functioning of the aging brain to the mild cognitive impairment that can be an early sign of Alzheimer’s disease.

Principal investigator(s): David Bennett, MD; Funding agency: National Institutes of Health Dates of grant/study: 1994 to 2016

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Study design involves a detailed assessment of risk factors for AD in older persons without known dementia who agree to annual clinical evaluation and organ donation at the time of death. “By participating in the Memory and Aging Project, you join us in our efforts to better understand, treat and hopefully prevent these problems associated with abnormal aging. Study participants must agree to yearly testing and organ donation, since Alzheimer’s disease can be best documented by examining brain tissue under a microscope after death.”

Principal investigator(s): David Bennett, MD; Funding agency: National Institute on Aging; Dates of grant/study: 2001 to 2019

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The Minority Aging Research Study is a unique study designed for older African Americans. The goal is to learn how to prevent common problems associated with aging, including poor memory, slowed walking and weakness. We want to understand why we lose certain abilities as we get older, figure out how to improve these abilities, and discover ways to prevent aging-related problems from affecting our children and grandchildren.

Principal investigator(s): Lisa Barnes, PhD; Funding agency: National Institute of Aging; Dates of grant/study: 2004 to 2021

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Latino CORE Study

The goal is to learn about the aging process and the risk factors for Alzheimer’s disease of older Latino adults.

Principal investigator(s): David Bennett, MDFunding agency: National Institute on Aging; Dates of grant/study: 2015 to 2021

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Mediterranean-DASH Intervention From Neurodegenerative Delay (MIND) Diet Intervention Trial

The MIND Diet is combination of Mediterranean and DASH diets, focusing on “brain-healthy food groups.” Although many factors determine who gets Alzheimer’s Disease and who doesn’t, this trial is looking at the effects of this diet in providing more protection from the disease.

Principal investigator(s): Martha Clare Morris, ScDFunding agency: National Institute on Aging; Dates of grant/study: 2017 to 2020

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Rush University Medical Center is a member of the Institute for Translational Medicine (ITM) in partnership with the University of Chicago. ITM is a network of more than 60 NIH-supported sites across the country working to slash the time it takes to develop and share new treatments and health approaches. ITM works with you and for you to make participating in health research easy, so that together we improve health care for all. To learn more, please visit the ITM website.